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COVID-19 Infection Risk, Elective Arthroplasty and Surgical Complications and COVID-19 Vaccination: Correspondence

Open AccessPublished:November 03, 2022DOI:https://doi.org/10.1016/j.artd.2022.10.014
      Dear Editor,
      we would like to discuss " COVID-19 Infection Risk Following Elective Arthroplasty and Surgical Complications in COVID-19 Vaccinated Patients: A Multicenter Comparative Cohort Study [
      • Mirghaderi S.P.
      • Salimi M.
      • Moharrami A.
      • Hosseini-Dolama R.
      • Mirghaderi S.R.
      • Ghaderi M.
      • Motififard M.
      • Mortazavi S.M.J.
      COVID-19 Infection Risk Following Elective Arthroplasty and Surgical Complications in COVID-19 Vaccinated Patients: A Multicenter Comparative Cohort Study.
      ].” The immunization, according to Mirghaderi et al., does not guarantee that a patient would not get COVID-19 following arthroplasty surgery, especially in an area with a high risk of COVID-19. We believe that moderate COVID-19 measures may be necessary even in vaccinated patients [
      • Mirghaderi S.P.
      • Salimi M.
      • Moharrami A.
      • Hosseini-Dolama R.
      • Mirghaderi S.R.
      • Ghaderi M.
      • Motififard M.
      • Mortazavi S.M.J.
      COVID-19 Infection Risk Following Elective Arthroplasty and Surgical Complications in COVID-19 Vaccinated Patients: A Multicenter Comparative Cohort Study.
      ].
      We can all agree that providing a COVID-19 vaccine is a fantastic idea. Several factors, such as the vaccinee's past co-morbidity, the kind of COVID-19, the manner of vaccine administration, and the local epidemiology of SARS-CoV-2, are examples. In the absence of clinical signs, the prevalent occurrence of asymptomatic COVID-19 could also be a role [
      • Joob B.
      • Wiwanitkit V.
      Letter to the Editor: Coronavirus Disease 2019 (COVID-19), Infectivity, and the Incubation Period.
      ]. Testing is frequently skipped to rule out a previous, asymptomatic COVID-19 infection. Only having a history of previous illnesses is insufficient. Laboratory testing must be performed as needed. To better identify the underlying immunological difficulties that a vaccine recipient is experiencing, certain laboratory testing should be used. Examining the underlying immunological abnormalities of vaccination recipients on a regular basis helps one to forecast the efficacy of the COVID-19 vaccine.
      . This is an important consideration when determining the efficacy or safety of a vaccination.
      Despite the fact that data on pre-vaccination health or immunological status are occasionally lacking, various clinical articles have demonstrated the efficacy, safety, or clinical significance of the COVID-19 vaccine. Furthermore, the possibility of cross-contamination with an undetected SARS-Co-V2 infection cannot be completely eliminated. Another recent study [
      • Čiučiulkaitė I.
      • Möhlendick B.
      • Thümmler L.
      • Fisenkci N.
      • Elsner C.
      • Dittmer U.
      • Siffert W.
      • Lindemann M.
      GNB3 c.825c>T polymorphism influences T-cell but not antibody response following vaccination with the mRNA-1273 vaccine.
      ] discovered a relationship between inherited genetic variation and vaccine recipients' immunological reaction. If additional research is planned, the impact of the genetic polymorphism should be assessed.

      Conflict of interest

      none

      References

        • Mirghaderi S.P.
        • Salimi M.
        • Moharrami A.
        • Hosseini-Dolama R.
        • Mirghaderi S.R.
        • Ghaderi M.
        • Motififard M.
        • Mortazavi S.M.J.
        COVID-19 Infection Risk Following Elective Arthroplasty and Surgical Complications in COVID-19 Vaccinated Patients: A Multicenter Comparative Cohort Study.
        Arthroplast Today. 2022 Sep 27; (Online ahead of print)https://doi.org/10.1016/j.artd.2022.09.005
        • Joob B.
        • Wiwanitkit V.
        Letter to the Editor: Coronavirus Disease 2019 (COVID-19), Infectivity, and the Incubation Period.
        J Prev Med Public Health. 2020 Mar; 53: 70
        • Čiučiulkaitė I.
        • Möhlendick B.
        • Thümmler L.
        • Fisenkci N.
        • Elsner C.
        • Dittmer U.
        • Siffert W.
        • Lindemann M.
        GNB3 c.825c>T polymorphism influences T-cell but not antibody response following vaccination with the mRNA-1273 vaccine.
        Front Genet. 2022 Aug 29; 13932043

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